中南大学细胞生物学硕士。深圳中山妇产医院生殖医学临床研究中心研究员。
擅长领域：目前主要从事女性生殖疾病的分子遗传学病因探究、多囊卵巢综合征的子宫内膜和卵泡液研究、卵巢功能不全的病因学以及不明原因流产的作用分子机制研究等方面的研究。
学术任职：American Journal of Reproductive Immunology审稿人
学术成果：
一、主持或参加科研项目(课题)及人才计划项目情况(按时间倒序排序)：
1. 深圳市科技创新委员会基础研究-面上项目、JCYJ20220530172814032、SIRT1缓解高雄激素诱导的PCOS子宫内膜基质细胞氧化应激的机制研究、2022/10-2025/10、在研、主持。
2. 深圳市科技创新委员会基础研究-面上项目、JCYJ20210324123412035、高雄激素通过调节丙酮酸脱氢酶激酶4的表达抑制PCOS子宫内膜蜕膜化的分子机制、2021/10-2024/10、在研、参与。
3. 中华医学会临床医学科研专项资金项目、18010130742、LncRNA EPB41L4A-AS1通过调控绒毛组织代谢重编程引起早期反复自然流产的分子机制研究、2019/06-2021/06、结题、参与。
4. 国家自然科学基金-面上项目、81672632、PIK3CG在Claudin-low乳腺癌中的作用机制及干预研究、2017/01-2020/12、结题、参与。
二、代表性研究成果和学术奖励(分类按时间倒序排序)：
1. 期刊论文
(1) Su Liu, Sainan Zhang, Ling Hong, Lianghui Diao, Songchen Cai, Tailang Yin*, Yong Zeng*. Characterization of progesterone-induced dendritic cells in metabolic and immunologic reprogramming. Journal of Reproductive Immunology, 2023, 159: 104128.
(2) Su Liu#, Ling Hong#, Ruochun Lian, Shan Xiao, Yuye Li, Lianghui Diao*, Yong Zeng*. Transcriptomic Analysis Reveals Endometrial Dynamics in Normoweight and Overweight/Obese Polycystic Ovary Syndrome Women. Frontiers in Genetics, 2022, 13:874487. doi: 10.3389/fgene.2022.874487.
(3) Su Liu, Ling Hong, Meilan Mo, Shan Xiao, Xuejin Wang, Xinfeng Fan, Sainan Zhang, Lianghui Diao*, Yong Zeng*. Association of antimüllerian hormone with polycystic ovarian syndrome phenotypes and pregnancy outcomes of in vitro fertilization cycles with fresh embryo transfer. BMC Pregnancy and Childbirth, 2022, 22:171. doi: 10.1186/s12884-022-045518-0.
(4) 肖珊, 莫美兰, 刘苏, 洪玲等.多囊卵巢综合征患者拮抗剂方案中早发LH升高对IVF-ET临床结局的影响[J]. 生殖医学杂志, 2022, 31(1): 6-12.
(5) Sainan Zhang#, Su Liu#*, Ling Hong, Xiaohui Wang, Lianghui Diao, Songchen Cai, Tailang Yin* and Yong Zeng*. Identification of Profound Metabolic Alterations in Human Dendritic Cells by Progesterone Through Integrated Bioinformatics Analysis. Front. Immunol 2021; 12: 806110.
(6) Ling Hong#, Yuanchang Zhu#, Su Liu, Tonghua Wu, Yuye Li, Lijun Ye, Lianghui Diao*, Yong Zeng*. Multi-omics reveals a relationship between endometrial amino acid metabolism and autophagy in women with recurrent miscarriage. Biol Reprod. 2021, 28. doi: 10.1093/biolre/ioab101.
(7) Liu Su#, Hong Ling#, Mo Meilan, Xiao Shan, Chen Cong, Li Yuye, Lian Ruochun, Wang Xuejin, Cai Songchen, Diao Lianghui*, Zeng Yong*. Evaluation of endometrial immune status of polycystic ovary syndrome. J Reprod Immunol, 2021. 144, 103282.
(8) Su Liu, Ling Hong, Yuye Li, Ruochun Lian, Xiaohui Wang and Yong Zeng*. Association between endometrial indoleamine 2,3-dioxygenase expression level and pregnancy outcomes in women undergoing first in vitro fertilization treatment. BMC Pregnancy and Childbirth 21, 33 (2021). https://doi.org/10.1186/s12884-020-03511-9.
(9) Lijun Ye#, Wensi Huang#, Su Liu, Songchen Cai, Ling Hong, Weiqiang Xiao, Kristin Thiele, Yong Zeng, Mingzhe Song*, Lianghui Diao*. Impacts of Immunometabolism on Male Reproduction. Front. Immunol., 2021. https:// doi.org/10.3389/fimmu.2021.658432.
(10) Yiqiu Wei#, Jinli Ding#, Jianan Li, Songchen Cai, Su Liu, Ling Hong, Tailang Yin*, Yan Zhang*, Lianghui Diao*. Metabolic Reprogramming of Immune Cells at the Maternal-Fetal Interface and the Development of Techniques for Immunometabolism. Front Immunol 2021; 12: 717014.
(11) Qian Zhang, Yiwen Pan, Xiaochun Ma, Hao Yang, Jun Chang, Ling Hong, Huiwen Yan, Shubing Zhang*. Elevated secretion of aldosterone increases the risk of atherosclerosis complications by potentiating the Ox-LDL-induced dysfunction of HUVEC. Cell Journal, 2021, 23:1
(12) Jun chang, Ling Hong, Yaozhong Liu, Yiwen Pan, Hao Yang, Wenrui Ye, Keli Xu, Zhijian Li*, and Shubing Zhang*. Targeting PIK3CG in Combination with Paclitaxel as a Potential Therapeutic Regimen in Claudin-Low Breast Cancer, Cancer Management and Research (2020) 12, 2641-2651.
(13) Su Liu, Meilan Mo, Shan Xiao, Longfei Li, Xiuyu Hu, Ling Hong, Linlin Wang, Ruochun Lian, Chunyu Huang, Yong Zeng* and Lianghui Diao*. Pregnancy Outcomes of Women with Polycystic Ovary Syndrome for the First In Vitro Fertilization Treatment: A Retrospective Cohort Study With 7678 Patients. Front Endocrinol, 2020. 11:575337. doi: 10.3389/fendo.2020.575337.
(14) Tonghua Wu, Yuanchang Zhu, Ling Hong, Qi Lin, Chunmei Chen, Jing Yang, Lijun Ye, Wensi Huang, Yong Zeng(*). Evaluation of two aneuploidy screening tests for chorionic villus samples: Multiplex ligation-dependent probe amplification and fluorescence in situ hybridization, Molecular and Cellular Probes (2019) 46, 101422. doi: 10.1016/j.mcp.2019.101422.
(15) 洪玲. Notch信号通路中关键***Lunatic Fringe功能的研究进展. 国际遗传学杂志 (2018) 5, 373-379.
2. 会议论文
(1) 2019年11月13日-16日，中国福州，中华医学会第十三次全国生殖医学学术会议，壁报交流，题目：男女罗伯逊易位引起的不同临床效应比较分析.
(2) 2020年11月26日-29日，中国珠海，中华医学会第十四次全国生殖医学学术会议，壁报交流，题目：不同质量指数多囊卵巢综合征患者子宫内膜的转录组学差异性特征分析.
(3) 2022年5月22日-26日，美国纳什维尔，第41届美国生殖免疫学会年会，口头汇报，题目：Androgen excess inhibits decidualization in human endometrial stromal cells via AMPK/SIRT1/PDK4 pathway.